Massachusetts Pharmacy Technician License Practice Test

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Prepare for the Massachusetts Pharmacy Technician License Exam. Study with flashcards and multiple choice questions, each providing hints and thorough explanations to ensure exam readiness!

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Which of the following is classified as a COX-2 inhibitor among NSAIDs?

  1. Ibuprofen

  2. Celecoxib

  3. Aspirin

  4. Naproxen

The correct answer is: Celecoxib

Celecoxib is classified as a COX-2 inhibitor among nonsteroidal anti-inflammatory drugs (NSAIDs). COX-2 inhibitors are specifically designed to target the COX-2 enzyme, which is associated with inflammation and pain, while sparing the COX-1 enzyme that protects the stomach lining. This selective inhibition is intended to reduce gastrointestinal side effects commonly associated with traditional NSAIDs, which inhibit both COX-1 and COX-2 enzymes. The other options mentioned are traditional NSAIDs, which do not selectively inhibit COX-2. Ibuprofen, aspirin, and naproxen all affect both COX-1 and COX-2 enzymes, leading to potential gastrointestinal issues due to COX-1 inhibition. This distinction is crucial when considering the side effect profiles of different NSAIDs and the therapeutic decisions made in clinical practice.

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