Massachusetts Pharmacy Technician License Practice Test

Which drug is primarily indicated to treat hyperuricemia?

1. Ibuprofen

2. Colchicine

3. Prednisone

4. Acetaminophen

The correct answer is: Colchicine

Colchicine is primarily indicated to treat hyperuricemia because it specifically targets the inflammation associated with gout, which is a condition characterized by elevated levels of uric acid in the blood. The mechanism of colchicine involves disrupting the inflammatory response that occurs due to the crystallization of urate in the joints. By doing so, it helps alleviate the pain and swelling associated with gout attacks, which are directly related to hyperuricemia. The other drugs listed do not have a primary action in treating hyperuricemia. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation but does not directly decrease uric acid levels. Prednisone is a corticosteroid that can reduce inflammation but is typically used in more severe or chronic cases and is not specifically indicated for hyperuricemia. Acetaminophen is an analgesic that reduces pain and fever but does not address the underlying cause of high uric acid levels. Thus, colchicine is the most appropriate choice for the management of hyperuricemia and its related conditions.