Massachusetts Pharmacy Technician License Practice Test

Under what condition can generic drugs be substituted for brand-name drugs?

1. Only if the prescriber allows it

2. Whenever there is a price difference

3. Based on patient preference

4. When the pharmacy runs out of stock

The correct answer is: Only if the prescriber allows it

Generic drugs can be substituted for brand-name drugs primarily under the condition that the prescriber allows it. This is rooted in legal and ethical guidelines, as the prescriber has the responsibility to ensure that the patient receives the most appropriate medication based on their specific health needs. If a prescriber indicates "dispense as written" on the prescription, it is a clear directive to use the brand-name medication only. This practice is also supported by the fact that while generics are required to have the same active ingredients, dosage form, strength, and route of administration as their brand-name counterparts, the healthcare provider may have specific reasons for selecting a particular brand based on factors such as the patient's unique response to a medication, allergies, or previous adverse effects. Substitutions based solely on price differences, patient preferences, or stock availability without prescriber consent could potentially lead to treatment complications or ineffectiveness. Hence, prescriber's permission is crucial to ensure safe and effective patient care.